In Anlehnung an die VARC-2-Kriterien sind schwere Blutungen zu dokumentieren:
„Overt bleeding either associated with a drop in the hemoglobin
level of at least 3.0 g/dL or requiring transfusion of 2 or 3 units of
whole blood/RBC, or causing hospitalization or permanent injury, or
requiring surgery“
Quelle: Updated standardized endpoint definitions for transcatheter
aortic valve implantation: The Valve Academic Research Consortium-2
consensus document, Kappetein, A. et al., The Journal of Thoracic and
Cardiovascular Surgery, January 2013